Fenben lab fenbendazol is an anthelmintic (kills parasitic worms) used to treat various kinds of roundworm, hookworm, whipworm and some tapeworm infections in dogs and cats. It’s also being used by people as part of a cancer treatment known as the Joe Tippens Protocol. It’s been found to kill some kinds of cancer cells in the laboratory, and it has a very wide margin of safety. It’s also a compound with no serious side effects in animals and humans when taken as directed.
The Joe Tippens Protocol involves taking 222 mg of fenbendazole per day seven days a week. It’s available as a tablet or as an oral suspension and is typically given with food. It’s not a cure for cancer, but it does help people live longer and avoid the chemotherapy and radiation that many traditional cancer treatments require.
According to the information spread through social media, fenbendazole can have an anticancer effect by interfering with the formation of microtubules, a component of the protein scaffold that gives cells their shape and structure. Cells establish a framework called the mitotic spindle that separates identical copies of chromosomes during cell division (mitosis). The function of this structure is essential for ensuring that chromosomes are evenly separated. Drugs that interfere with the activity of microtubules block important cellular processes. Fenbendazole, a derivative of the benzimidazole class of compounds, has been shown to have these properties.
A new study found that combining fenbendazole with a diet rich in vitamins significantly inhibited the growth of human multiple myeloma cells in mice. This finding is consistent with other studies that have found fenbendazole and other benzimidazoles to be effective against multiple myeloma.
The study’s authors speculate that the antitumor effect observed in this study may be partially due to a higher concentration of vitamins than usual in the control diet. Vitamins in prepared diets deteriorate with time, and the study diet used during this experiment was nearing its expiration date (6 mo after manufacture) when it was replaced by the treatment diet. In contrast, the dietary supplement used in the initial observation of this tumor model was more recently purchased and had higher vitamin concentrations than normal.
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